# Dr. David Sinclair — the Biology of Slowing & Reversing Aging  - URL: https://share.snipd.com/episode/ed91555f-3365-4292-9335-440b0e47a946 ## Highlights - Longevity vs Anti Aging: Valid Ways to Talk about Aging as a Disease Key takeaways: - Longevity and anti-aging are academically similar terms, but 'anti-aging' has negative connotations due to misuse. - Aging is considered a disease and can lead to deterioration, illness, and death. - Aging is responsible for approximately 80-90% of heart disease and Alzheimer's cases. - Slowing down aging can prevent the onset of age-related diseases. - Reversing the aging process can potentially eliminate age-related diseases. - There is a need to shift focus from treating individual diseases to addressing aging as the root cause of multiple ailments. - No specific general phenomenon underlying aging is mentioned in the passage. Transcript: Speaker 1 Well, so longevity is the the more academic way we describe what we research. Anti aging is kind of the same thing, but it's got a bad rapbeau. It's been used by all bunch people that don't know what they're talking about. So i really don't like that term, anti aging. But aging as a disease and longevity are perfectly valid ways to talk about this subject. So let's talk about aging as a disease. When i started my research disease here at harvard medical school, it was considered, if there's something that's wrong with you, ah, and it's a rare has to be less than 50 % of the population, That's definitely a disease. And then people work their whole lives to try and cure that condition. And so i looked up what's the definition of aging, and it's as well, to deterioration and inhealth and sickness, and you can die from it. Typically you do ah, something that sounds pretty much like a disease. But the caviot is that if more than half the population gets this condition, aging put in a different bucket. Which is, first all, that's outrageous, cause it's justa totally arbitrary cut off. But think about this, that we're ignoring the major cause of all these diseases. Aging is 80 to 90 % the cause of heart disease, altsimes. If we didn't get old and our bodies stayed youthful, we would not get those diseases. And actually, what we're showing in my libels, if you turned the clock back in tissues, those diseases go away. So aging is the problem. And instead, through most of the last 200 years, we've been sticking bandates on diseases that have already occurred because of aging, and then it's too late. So there are a couple of things. One, as we want a slow aging down so we don't get those diseases. And when they do occur, don't you stick a bandate on reverse the age of the body, and then the diseases will go away. Speaker 2 That clarifies a lot for me. Thank you. Can we point to one fic general phenomenon in the body that underlies aging? ([Time 0:08:36](https://share.snipd.com/snip/d43a0d39-bf0c-407d-a565-8bab34f1c4b5)) - Longevity vs Anti-Aging: Exploring Aging as a Disease Key takeaways: - Longevity and anti aging are valid ways to discuss the research on aging. - Aging is considered a disease that causes deterioration, sickness, and death. - Aging is the major cause of diseases like heart disease and Alzheimer's. - Slowing down aging can prevent the occurrence of these diseases. - Reversing the aging process can eliminate the diseases that have already occurred. Transcript: Speaker 1 Well, so longevity is the the more academic way we describe what we research. Anti aging is kind of the same thing, but it's got a bad rapbeau. It's been used by all bunch people that don't know what they're talking about. So i really don't like that term, anti aging. But aging as a disease and longevity are perfectly valid ways to talk about this subject. So let's talk about aging as a disease. When i started my research disease here at harvard medical school, it was considered, if there's something that's wrong with you, ah, and it's a rare has to be less than 50 % of the population, That's definitely a disease. And then people work their whole lives to try and cure that condition. And so i looked up what's the definition of aging, and it's as well, to deterioration and inhealth and sickness, and you can die from it. Typically you do ah, something that sounds pretty much like a disease. But the caviot is that if more than half the population gets this condition, aging put in a different bucket. Which is, first all, that's outrageous, cause it's justa totally arbitrary cut off. But think about this, that we're ignoring the major cause of all these diseases. Aging is 80 to 90 % the cause of heart disease, altsimes. If we didn't get old and our bodies stayed youthful, we would not get those diseases. And actually, what we're showing in my libels, if you turned the clock back in tissues, those diseases go away. So aging is the problem. And instead, through most of the last 200 years, we've been sticking bandates on diseases that have already occurred because of aging, and then it's too late. So there are a couple of things. One, as we want a slow aging down so we don't get those diseases. And when they do occur, don't you stick a bandate on reverse the age of the body, and then the diseases will go away. ([Time 0:08:36](https://share.snipd.com/snip/ad50a3ce-e6cf-4cec-9ff5-4793f5172754)) - Longevity vs Anti-Aging: Exploring Aging as a Disease Key takeaways: - Longevity and anti aging are valid ways to discuss the research on aging. - Aging is considered a disease that causes deterioration, sickness, and death. - Aging is the major cause of diseases like heart disease and Alzheimer's. - Slowing down aging can prevent the occurrence of these diseases. - Reversing the aging process can eliminate the diseases that have already occurred. Transcript: Speaker 1 Well, so longevity is the the more academic way we describe what we research. Anti aging is kind of the same thing, but it's got a bad rapbeau. It's been used by all bunch people that don't know what they're talking about. So i really don't like that term, anti aging. But aging as a disease and longevity are perfectly valid ways to talk about this subject. So let's talk about aging as a disease. When i started my research disease here at harvard medical school, it was considered, if there's something that's wrong with you, ah, and it's a rare has to be less than 50 % of the population, That's definitely a disease. And then people work their whole lives to try and cure that condition. And so i looked up what's the definition of aging, and it's as well, to deterioration and inhealth and sickness, and you can die from it. Typically you do ah, something that sounds pretty much like a disease. But the caviot is that if more than half the population gets this condition, aging put in a different bucket. Which is, first all, that's outrageous, cause it's justa totally arbitrary cut off. But think about this, that we're ignoring the major cause of all these diseases. Aging is 80 to 90 % the cause of heart disease, altsimes. If we didn't get old and our bodies stayed youthful, we would not get those diseases. And actually, what we're showing in my libels, if you turned the clock back in tissues, those diseases go away. So aging is the problem. And instead, through most of the last 200 years, we've been sticking bandates on diseases that have already occurred because of aging, and then it's too late. So there are a couple of things. One, as we want a slow aging down so we don't get those diseases. And when they do occur, don't you stick a bandate on reverse the age of the body, and then the diseases will go away. ([Time 0:08:36](https://share.snipd.com/snip/7662bcb6-2a73-4863-8b8f-5754315167cc)) - Longevity vs Anti-Aging: Exploring Aging as a Disease Key takeaways: - Longevity and anti aging are valid ways to discuss the research on aging. - Aging is considered a disease that causes deterioration, sickness, and death. - Aging is the major cause of diseases like heart disease and Alzheimer's. - Slowing down aging can prevent the occurrence of these diseases. - Reversing the aging process can eliminate the diseases that have already occurred. Transcript: Speaker 1 Well, so longevity is the the more academic way we describe what we research. Anti aging is kind of the same thing, but it's got a bad rapbeau. It's been used by all bunch people that don't know what they're talking about. So i really don't like that term, anti aging. But aging as a disease and longevity are perfectly valid ways to talk about this subject. So let's talk about aging as a disease. When i started my research disease here at harvard medical school, it was considered, if there's something that's wrong with you, ah, and it's a rare has to be less than 50 % of the population, That's definitely a disease. And then people work their whole lives to try and cure that condition. And so i looked up what's the definition of aging, and it's as well, to deterioration and inhealth and sickness, and you can die from it. Typically you do ah, something that sounds pretty much like a disease. But the caviot is that if more than half the population gets this condition, aging put in a different bucket. Which is, first all, that's outrageous, cause it's justa totally arbitrary cut off. But think about this, that we're ignoring the major cause of all these diseases. Aging is 80 to 90 % the cause of heart disease, altsimes. If we didn't get old and our bodies stayed youthful, we would not get those diseases. And actually, what we're showing in my libels, if you turned the clock back in tissues, those diseases go away. So aging is the problem. And instead, through most of the last 200 years, we've been sticking bandates on diseases that have already occurred because of aging, and then it's too late. So there are a couple of things. One, as we want a slow aging down so we don't get those diseases. And when they do occur, don't you stick a bandate on reverse the age of the body, and then the diseases will go away. ([Time 0:08:36](https://share.snipd.com/snip/5a9dadbc-6f86-4461-9432-bc7a6eba22b4))