metadata: - source: https://www.trialsitenews.com/a/is-the-covid-19-vaccine-a-bioweapon-c778c1d4 - people: [[Ronald Kostoff]] --- # Article _Dr. Ronald N. Kostoff_ ## OVERVIEW Since December 2020, much of the USA population has received injections that purportedly guard against COVID-19 disease.  These injections, whose contents are still unknown and appear to vary by vial “lot”, have been termed “vaccines” by their promoters, and poisons, bioweapons, toxic substances, etc. by their opponents.  There is much we do not know about how these injectants were developed, and there is much we are learning about their modes of action (biological mechanisms) and impacts on human health.  Much of the evidence for the impacts of these injectants and their modes of action comes from published studies, analyses of adverse event tracking databases such as VAERS (Vaccine Adverse Events Reporting System), V-safe, Biologics Effectiveness and Safety System, Vaccine Safety Datalink, EudraVigilance (Europe), Coronavirus Yellow Card (UK), Japanese Adverse Drug Event Report (JADER) database, Database of Adverse Event Notifications (DAEN) (Australia), etc., and indirect tracking databases such as insurance claim databases (many countries), labor disability database (USA), UK New Claims for Personal Independence Payment, etc.  The evidence makes clear that those who received these injections have experienced much higher rates of myriad diseases and injuries and much higher adverse economic consequences than those who did not receive the injections. The focus of the opponents of 1) these injections and 2) the extreme measures taken during the “pandemic” (lockdowns, masking, social distancing, etc.) seems to have concentrated around whether these injections are in fact bioweapons, and whether they are part of a larger effort to depopulate the US and force compliance on the survivors.  This Op-ed will focus specifically on the biowarfare agent issue. ## Definition What are Bioweapons?  “Biological weapons disseminate disease-causing organisms or toxins to harm or kill humans, animals or plants.  They generally consist of two parts – a [weaponized agent and a delivery mechanism](https://disarmament.unoda.org/biological-weapons/about/what-are-biological-weapons/)”.  Labelling a disease-causing organism and its delivery system as a bioweapon implies intent.  The remainder of this Op-ed will show that administration of the COVID-19 “vaccine” was followed by injury and death to many humans.  Additionally, its myriad modes of action produced abnormalities we would expect to result in injury or death.  While we cannot prove intent at the present time, it is unclear how immunology and virology experts in the US Health agencies (e.g., CDC, FDA, NIH, etc.) and in their expert Advisory Committees would not know, or not have known, that these modes of action would produce massive levels of injury and death that would far outweigh any potential benefits. ## ANALYSIS There are many biological mechanisms resulting in damage following the COVID-19 vaccinations.  This Op-ed will focus on three key mechanisms whose adverse effects were well known years before the COVID-19 vaccines were distributed: 1) degradation and suppression of the immune system, potentially leading to i) increased numbers of, and more aggressive, cancers, ii) reactivation of dormant viruses, iii) increases in autoimmune diseases; 2) induction of pseudo-autoimmunity, leading to the destruction of myriad tissues and organs that are plainly observed on post-COVID-19 vaccination autopsy slides; 3) concentration of the lipid nanoparticle (LNP)-mRNA package in ovaries (among other organs), leading to the possibility of sterility, infertility, and fetal malformations or death. 1. Degradation and Suppression of the Immune System An article in the [Epoch times](https://www.theepochtimes.com/health/mrna-covid-vaccines-may-be-triggering-aggressive-turbo-cancers-in-young-people-experts-5375766?utm_source=partner&utm_campaign=vigilantf&src_src=partner&src_cmp=vigilantf) quotes Dr. William Makis on nine potential causes for the rapid increases of cancers observed globally, including the very aggressive “turbo cancers”.  Some of these causes will be referenced in this section, when appropriate. A1. Suppression of Toll-Like Receptors Dr. Makis states: “The current COVID-19 mRNA vaccines contain pseudouridine-modified mRNA, which attenuates or alters the activity of key proteins in the innate immune system, impairing cancer surveillance.  When activated, these key proteins, called toll-like receptors, can p[revent tumors from forming and growing](https://www.theepochtimes.com/health/mrna-covid-vaccines-may-be-triggering-aggressive-turbo-cancers-in-young-people-experts-5375766?utm_source=partner&utm_campaign=vigilantf&src_src=partner&src_cmp=vigilantf).”.  As stated in one of the references, “Upon entering cells, unmodified IVT mRNA becomes intrinsically immunogenic…..For many years, this challenge slowed down the development of mRNA therapeutics, especially mRNA-replacement strategies. For instance, it has been shown that when treated with unmodified IVT mRNA, dendritic cells promote a T-cell response…..The activation of Toll-like receptors (TLRs), concretely TLR3 (a member of the TLRs family), that can recognize double-stranded viral RNA, is one of the mechanisms behind this induction of immune response…..In another work, it was suggested that single-stranded RNA could also induce an immune response in cells. The authors in that work showed that HIV-derived uridine-rich single-stranded RNA could stimulate, via recognition by TLR7 and TLR8, dendritic cells to produce cytokines…..Later, it was further suggested that TLR7 could recognize uracil repeats in close proximity in the RNA…..To address this problem…..incorporating Ψ, as a replacement of uridine, into the IVT mRNA could **_suppress this immune response mechanism_**…..In a follow-up study…..Karikó et al. proposed that the inclusion of Ψ would be the crucial step for mRNA to mature as a therapeutic tool, both in gene replacement therapies and in mRNA vaccination…..Karikó et al. also suggested that while Ψ-modified mRNA could be preferable for mRNA vaccines, it would eventually require the co-administration of an adjuvant such as lipopolysaccharide or an immunostimulatory oligo. In this regard, it appears that LNPs played this immunoadjuvant role as both carriers and adjuvants for the approved COVID-19 mRNA vaccines…..Another work from the Karikó/Weissman lab suggested that Ψ-modified mRNA could be [more resistant to RNase L-mediated degradation”](https://pubmed.ncbi.nlm.nih.gov/34805188/).  A more recent review addresses the myriad approaches that have been used and proposed for [mRNA stabilization](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965532/).  In this document, “the recent progress in nanobiotechnology-enabled strategies for stabilizing mRNA and better delivery is reviewed. First, factors that destabilize mRNA are introduced. Second, nanobiotechnology-enabled strategies to stabilize mRNA molecules are reviewed, including molecular and nanotechnology approaches. The impact of formulation processing on mRNA stability and shelf-life, including freezing and lyophilization, are also briefly discussed.” Finally, a paper that addresses the role of TLRs in cancer states: “TLR activation in immune as well as cancer cells may prevent the formation and growth of a tumor. Nonetheless, under certain conditions, either hyperactivation or **_hypoactivation_** of TLRs supports the [survival and metastasis of a tumor.](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072551/#:~:text=TLR%20activation%20in%20immune%20as,and%20metastasis%20of%20a%20tumor)” Neither of the first two well-researched papers addresses the adverse consequences of 1) deliberately suppressing enzymes and other substances that could degrade the foreign mRNA or 2) allowing an encapsulated foreign mRNA to travel throughout the circulatory system to any tissue or organ in the body.  While this modification might have been necessary for a successful drug delivery system for any organ or tissue, it is difficult to see positive value for a vaccine. A2. Suppression of Type 1 Interferon Dr. Makis states: “Vaccination alters T-cell signaling that induces profound impairment in type 1 interferon and cancer surveillance.”  T-cells, a type of white blood cell, help the body’s immune system prevent cancer. Studies show that getting multiple shots increases the level of a particular antibody called IgG4, causing T-cell and interferon suppression, leading to an inability to keep cancer in check, Dr. Cole told The Epoch Times. “Everyone gets atypical cells in their body every day, and having a surveillance system is important, but when the surveillance system is shut off, that allows these cells to go haywire. How long it stays suppressed, nobody knows, and these are the studies NIH (the National Institutes of Health) should have been doing,” [said Dr. Cole](https://www.theepochtimes.com/health/mrna-covid-vaccines-may-be-triggering-aggressive-turbo-cancers-in-young-people-experts-5375766?utm_source=partner&utm_campaign=vigilantf&src_src=partner&src_cmp=vigilantf). A comprehensive article on suppression of Type 1 Interferon (among other issues) [states the following](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012513/): “IFNs play a critical role in both controlling viral proliferation and inducing antibody production. Central to both antiviral and anticancer immunity, IFN-α is produced by macrophages and lymphocytes when either is challenged with viral or bacterial infection or encounters tumor cells…..Impaired type I IFN signaling is linked to many disease risks, most notably cancer, as type I IFN signaling suppresses proliferation of both viruses and cancer cells by arresting the cell cycle, in part through upregulation of p53, a tumor suppressor gene, and various cyclin-dependent kinase inhibitors…..IFN-α also induces major histocompatibility (MHC) class 1 antigen presentation by tumor cells, causing them to be more readily recognized by the cancer surveillance system…..anticancer effects initiated by IFN-α expression…..occurs through both direct and indirect mechanisms. Direct effects include cell cycle arrest, induction of cell differentiation, initiation of apoptosis, activation of natural killer and CD8+ T cells, and others…..indirect anticancer effects are predominantly carried out through gene transcription activation of the Janus kinase signal transducer and activator of transcription (JAK/STAT) pathway…..IFN-α both initiates and orchestrates a wide range of cancer suppressing roles. Dunn et al…..showed that IFN-α plays an active role in cancer immunoediting, its locus of action being hematopoietic cells that are “programmed” via IFN-α binding for tumor surveillance. It is via the exceedingly complex interactions between type I IFNs and IRF7 and IRF9 in particular that a great deal of antiproliferative effects are carried out…..type I IFNs play a singularly important role in protective immunity against COVID-19 illness…..the SARS-CoV-2 spike glycoprotein modifies host cell exosome production. Transfection of cells with the spike protein's gene and subsequent SARS-CoV-2 spike protein production results in those cells generating exosomes containing microRNAs that suppress IRF9 production while activating a range of pro-inflammatory gene transcripts…..these vaccines are specifically designed to induce high and ongoing production of SARS-CoV-2 spike glycoproteins…..inhibition of IRF9 will suppress TRAIL and all its regulatory and downstream apoptosis-inducing effects. IRF9 suppression via exosomal microRNA should also be expected to impair the cancer-protective effects of BRCA2 gene activity…..BRCA2-associated cancers include breast, fallopian tube, and ovarian cancer for women, prostate and breast cancer for men, acute myeloid leukaemia in children, and others…..Vaccination has also been demonstrated to suppress both IRF7 and STAT2…..This can be expected to interfere with the cancer-protective effects of BRCA1…..Cancers associated with impaired BRCA1 activity include breast, uterine, and ovarian cancer in women; prostate and breast cancer in men; and a modest increase in pancreatic cancer for both men and women…..Reduced BRCA1 expression is linked to both cancer and neurodegeneration…..Given the universally recognized importance of optimally functioning BRCA1/2 for cancer prevention and given the central role of the TRAIL signal transduction pathway for additional cancer surveillance, the suppression of IRF7 and IRF9 through vaccination and subsequent SARS-CoV-2 spike glycoprotein production is extremely concerning for long-term cancer control in SARS-CoV-2 mRNA genetic vaccine injected populations.” A3. Reduction of IgG3 relative to IgG4 Dr. Makis states: “[The shift of the antibody IgG4 caused by repeated mRNA vaccination could create a tolerance for spike protein and impair the production of the antibodies IgG1 and IgG3 and cancer surveillance.](https://www.theepochtimes.com/health/mrna-covid-vaccines-may-be-triggering-aggressive-turbo-cancers-in-young-people-experts-5375766?utm_source=partner&utm_campaign=vigilantf&src_src=partner&src_cmp=vigilantf)”  COVID-19 mRNA vaccines increase the serum levels of IgG4.  The consequences of this impact are summarized through the following paper excerpts.  The first few were written pre-COVID-19 mRNA vaccine rollout, and show **_the problem was well-known before the vaccines were (officially) generated_**. A 2016 paper on IgG4 and cancer states: “Reports of IgG4 antibodies and IgG4+ B cells in different cancers suggest the **_involvement of IgG4 in tumor escape from immune surveillance_** through a number of potential mechanisms, [including IgG4 blockade of IgG1-mediated effector functions](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705142/)” A 2020 paper on the role of IgG4 in promoting cancer states: “Results In a cohort of patients with esophageal cancer we found that IgG4-containing B lymphocytes and IgG4 concentration were significantly increased in cancer tissue and IgG4 concentrations increased in serum of patients with cancer. Both were positively related to increased cancer malignancy and poor prognoses, that is, **_more IgG4 appeared to associate with more aggressive cancer growth_**. We further found that IgG4, regardless of its antigen specificity, inhibited the classic immune reactions of antibody-dependent cell-mediated cytotoxicity, antibody-dependent cellular phagocytosis and complement-dependent cytotoxicity against cancer cells in vitro…..We also found that IgG4 competed with IgG1 in reacting to Fc receptors of immune effector cells. Therefore, **_locally increased IgG4 in cancer microenvironment should inhibit antibody-mediated anticancer responses and help cancer to evade local immune attack and indirectly promote cancer growth_**…..We found that local application of IgG4 significantly accelerated growth of inoculated breast and colorectal cancers and carcinogen-induced [skin papilloma](https://jitc.bmj.com/content/8/2/e000661).” A 2020 paper on the role of IgG4 in tolerance in allergy and cancer states: “Among the four immunoglobulin G (IgG) subclasses, IgG4 is the least represented in serum of a healthy human and it is considered an “odd” antibody……these characteristics support anti-inflammatory roles of IgG4 leading to immune tolerance. Under conditions of chronic antigenic stimulation and Th2-type inflammation, both tissue and serum IgG4 levels are increased…..in allergen immunotherapy IgG4 can confer a protective role as a “blocking” antibody and safeguard from subsequent allergen exposure, while **_IgG4 can confer immunomodulatory functions to support malignancy_**…..IgG4 have a Janus-faced role, favorable in allergy but [**_detrimental in cancer_**](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404042/).” A 2022 paper on increase in IgG4 after mRNA vaccination states: “several months after the second vaccination, **_SARS-CoV-2–specific antibodies were increasingly composed of noninflammatory IgG4_**, which were further boosted by a third mRNA vaccination and/or SARS-CoV-2 variant breakthrough infections.  IgG4 antibodies among all spike-specific IgG antibodies rose, on average, from 0.04% shortly after the second vaccination to 19.27% late after the third vaccination.  This induction of IgG4 antibodies was not observed after homologous or heterologous SARS-CoV-2 vaccination with [adenoviral vectors](https://www.science.org/doi/10.1126/sciimmunol.ade2798)." A 2023 paper on mRNA vaccines states: “repeated immunization of naïve individuals with the mRNA vaccines **_increased the proportion of the IgG4 subclass over time_** which might influence the [long-term Ab effector functions.](https://pubmed.ncbi.nlm.nih.gov/36713457/))”. Finally, a 2023 paper on the induction of immune tolerance by IgG4 states: “recent investigations have found abnormally high levels of IgG4 in people who were administered two or more injections of the mRNA vaccines…..Overall, there are three critical factors determining the class switch to IgG4 antibodies: excessive antigen concentration, repeated vaccination, and the type of vaccine used…..emerging evidence suggests that the reported increase in IgG4 levels detected after repeated vaccination with the mRNA vaccines may not be a protective mechanism; rather, it constitutes an immune tolerance mechanism to the spike protein that could promote unopposed SARS-CoV2 infection and replication by suppressing natural antiviral responses. **_Increased IgG4 synthesis due to repeated mRNA vaccination_** with high antigen concentrations may also cause autoimmune diseases, and **_promote cancer growth_** and autoimmune myocarditis in [susceptible individuals.](https://pubmed.ncbi.nlm.nih.gov/37243095/))” A4. Impact on Tumor Suppressor Protein p53 and Genomic Transposable Element LINE-1 Dr. Makis states: “The spike protein produced by the body after COVID-19 mRNA vaccination may interfere with important tumor suppressor proteins—P53, BRCA 1, and two tumor [suppressor genes](https://www.theepochtimes.com/health/mrna-covid-vaccines-may-be-triggering-aggressive-turbo-cancers-in-young-people-experts-5375766?utm_source=partner&utm_campaign=vigilantf&src_src=partner&src_cmp=vigilantf).”  A 2023 study addressing potential health risks of [mRNA-based vaccine therapy](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876036/) states: “a recent study that used hepatic cancer cells…..showed that the Pfizer/BioNTech vaccine mRNA BNT162b2 can undergo reverse-transcription within the cytoplasm of human cells and enter the nucleus following the activation of LINE-1, a genomic transposable element (TE). Genomic TEs, which comprise endogenous retroviruses (ERVs), long interspersed nuclear elements (LINEs), short interspersed nuclear elements (SINEs), and DNA transposons, are repetitive sequences that, when activated, copy themselves or other sequences and insert these copies into the genome…..aberrant expression of TEs has been associated with various diseases, from cancer to autoimmune disorders…..an independent study addressed whether the same phenomenon of reverse transcription and nuclear entry could be observed for vaccine mRNA. Using a human hepatic cell line (Huh7) and the Pfizer/BioNTech mRNA vaccine…..found that, indeed, the exogenous mRNA activates both ORFs of LINE-1, leading to both reverse transcription and nuclear transposition of the full length vaccine mRNA (BNT162b2) that encodes for the full SARS-CoV-2 Spike glycoprotein…..Reverse transcription occurred in as little as six hours post vaccine exposure, and the reverse-transcribed BNT162b2 cDNA was found to enter the cell nucleus…..LINE-1 transcription and protein expression was higher in the cancer cells exposed to BNT162b2 mRNA than in the cancer cells that received only saline solution…..suggesting that reverse transcription and nuclear transposition of the vaccine mRNA was not due to LINE-1 already being active in the cancer cell line…..there are no scientifically valid and biologically relevant reasons to assume that the same phenomenon could not occur in somatic cells of a person that receives the mRNA vaccine…..Given that LINE-1 transposition of copied sequences requires cleavage of both strands of the genomic DNA (DSB), unsilencing its activity can cause double-strand DNA breaks in germ-line and somatic cells…..**_In many cancer cells, LINE-1 activity is known to be correlated with p53 mutations and copy number alterations…..that are key to carcinogenesis, particularly in breast, ovarian, endometrial and colon cancers._** Other tissues can be similarly affected. For instance, a study of hepatitis C virus (HCV) cell transformation showed that as a result of sustained inflammation from chronic infection with HCV, LINE-1 expression is activated before oncogenic transformation, and that unsilenced LINE-1 contributes to genomic instability of the hepatocellular carcinoma, even after viral clearance…..Thus, **_unsilenced LINE-1 in somatic tissues that are expected vaccine targets (i.e. dendritic cells, lymph nodes, muscle cells) and unintended vaccine targets (e.g. liver, adrenal glands, spleen, ovaries, and brain)…..could conceivably increase the risk of genotoxicity and carcinogenesis in those tissues_**, and given that newly inserted copies of TE sequences can be transmitted to each successive cellular generation and modify the somatic human genome…..sustained activity of LINE-1 from persistent vaccine mRNA could be important for carginogenesis…..**_the risk would conceivably increase with each dose received_**. These molecular phenomena would expectedly be more frequent in intended and unintended vaccine target cells with intrinsic high levels of LINE-1 expression…..glial cells…..T-lymphocytes……senescent cells…..cells with reduced DNA damage repair mechanisms. Susceptibility would be particularly high for individuals with suppressed or suboptimal cellular adaptive immune responses, or those with neuropsychiatric diseases, where LINE-1 activity is abnormally high” A5. Spike Protein Interference with DNA Repair Mechanisms. Dr. Makis states: “The spike protein may interfere with DNA repair mechanisms”.  He references the [following article](https://www.sciencedirect.com/science/article/pii/S1383574222000011?via%3Dihub): As stated in the article, “these viruses can induce DNA damage, genomic instability, and cell cycle deregulation during their replication in mammalian cells…..the induction of DNA damage and aberrant DNA repair mechanisms are related to the development of chronic diseases such as cancer, diabetes, neurodegenerative disorders, and atherosclerosis”.  The inference is that the spike protein induced by the mRNA injection could have similar effects. A6.  Contaminants in COVID-19 Vaccines A6a.  Vaccines contaminated with Plasmid DNA containing SARS-CoV-2 spike protein Dr. Makis states: “Pfizer and Moderna vials found to be contaminated with plasmid DNA containing SARS-CoV-2 spike protein may integrate into the human genome.”  The [article he references](https://doctors4covidethics.org/covid-19-mrna-vaccines-contain-excessive-quantities-of-bacterial-dna-evidence-and-implications/) states: “The presence of contaminating plasmid DNA in Pfizer’s and Moderna’s mRNA vaccines entails severe health risks, in addition to those which were already known and understood. Preeminent among these risks are the prolonged expression of spike protein, which may lead to correspondingly prolonged and more destructive autoimmune-like inflammation, and the **_induction of malignant disease after chromosomal integration of the plasmid DNA_**.” A6b. Simian virus 40 (SV40) in DNA discovered in Pfizer mRNA vaccine vials Dr. Makis states: “The presence of the simian virus 40 (SV40) in DNA discovered in Pfizer mRNA vaccine vials may lead to cancers—most notably, non-Hodgkin lymphoma and other lymphomas—as it did with SV40-contaminated polio vaccines.”  The [first article he references](https://www.theepochtimes.com/health/green-monkey-dna-found-in-covid-19-shots-5317587?utm_source=open&utm_medium=search) states: “Microbiologist Kevin McKernan—a former researcher and team leader for the MIT Human Genome Project—has discovered massive DNA contamination in the mRNA COVID-19 shots, including simian virus 40 (SV40) promoters. SV40 has been linked to cancer in humans, including mesotheliomas, lymphomas, and cancers of the brain and bone. In 2002, the Lancet published evidence linking polio vaccines contaminated with SV40 to Non-Hodgkin’s lymphoma. According to the authors, the vaccine may be responsible for up to 50 percent of the 55,000 Non-Hodgkin’s lymphoma cases diagnosed each year. The level of contamination varies depending on the platform used to measure it, but no matter which method is used, the level of DNA contamination is significantly higher than the regulatory limits in both Europe and the United States. The highest level of DNA contamination found was 30 percent. The finding of DNA means the mRNA COVID-19 shots may have the ability to alter the human genome.” The second article [Dr. Makis references](https://pubmed.ncbi.nlm.nih.gov/15202523/) states: “We conclude that SV40 is significantly associated with some types of NHL and that lymphomas should be added to the types of human cancers associated with SV40”. A7. Enhanced expression of PD-L1 In a [Letter to the Editor](https://www.sciencedirect.com/science/article/pii/S0278691523003009), Seneff et al address the impacts of enhanced expression of programmed death ligand 1 (PD-L1) on the surface of immune cells following the COVID-19 vaccines. “expression of programmed death ligand 1 (PD-L1) on the surface of immune cells is significantly increased two days after the second vaccine…..Elevated PD-L1 on immune cells is a known risk factor for poor outcome in cancer patients, and cancer therapies that suppress PD-L1 are becoming popular as treatment options…..PD-L1 binding to PD-1 present on cancer cells inhibits T cells’ ability to kill cancer cells, mediating tumor immune escape”. The following summarizes the section of degradation and suppression of the immune system.  Seven broad factors (that degrade and suppress the immune system) resulting from COVID-19 vaccination were identified, and many more could have been addressed.  Any one of these factors occurring in isolation should cause concern about the potential for cancer.  Potential co-occurrence of all seven is alarming, and the probability of serious disease appears to increase with each additional shot. 1. Induction of Pseudo-Autoimmunity The following description of the induction of pseudo-autoimmunity was excerpted from an Op-ed on the COVID-19 vaccine-induced adverse effects on the [endocrine system](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-endocrine-events-rare-b4f0ecca).  However, it applies equally well to the other major systems in the body (cardiovascular, immune, circulatory, neural, etc.).  “The COVID-19 mRNA vaccines are injected in the deltoid muscle, and a fraction enters the bloodstream directly or indirectly ([Link#1](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241425/); [Link#2](https://pubmed.ncbi.nlm.nih.gov/35884842/)).  The mRNA that enters the bloodstream can survive because of protection by the LNP encapsulation.  As the Pfizer pharmacovigilance [studies showed](https://pdfhost.io/v/XM2al7Hi._Pfizer_report_Japanese_governmentjaenpdf.pdf), the LNP package concentrates in numerous organs. The damage to the blood vessels (and then to the tissues and organs) has been described most eloquently in a video by [Dr. Sucharit Bhakdi](https://doctors4covidethics.org/the-covid-vaccines-were-designed-to-fail-nov-25th-2021/), a world-renowned microbiologist: “the vaccines cause cells deep inside our body to express the viral spike protein, which they were never meant to do by nature. Any cell which expresses this foreign antigen on its surface will come under attack by the immune system, which will involve both IgG antibodies and cytotoxic T-lymphocytes. This may occur in any organ, but the damage will be most severe in vital organs.”…..What are some of the mechanisms shown to contribute to COVID-19 vaccine-induced autoimmunity?  “Multiple underlying mechanisms have been proposed for vaccine-induced autoimmunity, but the main mechanisms that have garnered validation include **_molecular mimicry; upregulation of immunological pathways, leading to vigorous production of pro-inflammatory cytokines; generation of autoantibodies; and the role of adjuvants in [triggering immune response](https://www.degruyter.com/document/doi/10.2478/rir-2022-0019/html?lang=en)_**”.  Also see  ([Link#1](https://pubmed.ncbi.nlm.nih.gov/36727031/); [Link#2](https://pubmed.ncbi.nlm.nih.gov/35169778/); [Link#3](https://pubmed.ncbi.nlm.nih.gov/34957554/); [Link#4](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979721/)) Further, consider the following definition of [autoimmunity/autoimmune disease](https://autoimmune.org/resource-center/about-autoimmunity/). “Some lymphocytes are capable of reacting against self, resulting in an autoimmune reaction. Ordinarily these lymphocytes are suppressed. Autoimmunity occurs naturally in everyone to some degree; and in most people, it does not result in diseases. **Autoimmune diseases occur when…..there is an alteration in some body tissue so that it is no longer recognized as “self” and is thus attacked.”**  There is an overlap between this part of the definition of autoimmune disease and Dr. Bhakdi’s statement: **“**Any cell which expresses this foreign antigen on its surface will come under attack by the immune system, which will involve both IgG antibodies and cytotoxic T-lymphocytes**”.**  The spike protein is the “foreign antigen on its surface” that alters the body tissue so that it is no longer recognized as “self”.  That means **_one aspect of the fundamental mode of operation of the COVID-19 vaccine could be perceived as contributing to the production of autoimmune disease_**.  If the spike protein has been expressed on the glands and other tissues and organs in the endocrine system, then adverse vaccine events will be generated in the endocrine system.  Many of the resulting diseases/disorders will have an autoimmune component because of the fundamental mode of operation of the spike protein (e.g., Autoimmune Thyroiditis, Autoimmune Hepatitis, Latent Autoimmune Diabetes in Adults, Autoimmune Pancreatitis, etc.).  Based on this biological mechanism, one might expect that the mass COVID-19 vaccination that has occurred might have added impact on onset and exacerbation of autoimmune diseases, including the autoimmune component of those endocrine diseases/disorders that have such a component.  A recent study showed that this is [indeed true](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-autoimmune-events-rare-8c55ed90). Again, because of the incubation time of many autoimmune diseases, years may be required to ascertain the full impact of the COVID-19 “vaccines” on the emergence of autoimmune (and endocrine) diseases: “Incubation time for different autoimmune diseases varies,” Shoenfeld said. “There are studies that show that the incubation time for lupus, for instance, might be more than 10 years. With a disease called ascending cholangitis, the incubation time can be up to [25 years.](https://www.drugtopics.com/view/new-onset-autoimmune-diagnoses-after-covid-19)”  “Autopsies have been the most credible source of information about the extent of the COVID-19 vaccine-induced damage, although they have been discouraged by governments around the world.  Some that [have been made available](https://www.bitchute.com/video/ljSS9LrKymZo/) show the extent of the damage in detail, and confirm the theory of damage expressed by Dr. Bhakdi and many others.  Different organs may receive the bulk of the damage in different individuals.  Typically, the autopsies show the spike protein infiltration into an organ (or tissue), the rupture of the endothelium, and the infiltration of the lymphocytes (which attack the cells that express the spike protein on the surface and thereby damage the organ (or tissue)).  This infiltration of spike protein appears to be a classic convection-diffusion process, with convection mainly through the bloodstream and diffusion through the tissues/organs.  As long as the body continues to function like a spike protein “factory” (which appears to be one consequence of the injection), the infiltration of spike protein and associated damage will continue.  With the addition of periodic boosters, the spike protein “factory” is replenished, and the damage will continue to spread.  It is difficult for me to see how anyone who has been injected with a **_functional_** mRNA vaccine can avoid this damage, and the associated adverse effects on lifespan.” A recent article on immune response and molecular mechanisms of cardiovascular adverse effects of spike proteins from SARS-CoV-2 and [mRNA vaccines](https://www.mdpi.com/2227-9059/11/2/451) states: “the mRNA vaccine “theory” neglects the possibility that any cell producing the Spike protein and displaying it on its membrane (associated or not with MHC-I) will be attacked and destroyed by CD8+T cells. The severity of the consequences for the host following the vaccination will depend on the type and number of cells affected and the tissue where the reaction occurs. For example, myocarditis is considered an adverse reaction to mRNA vaccination…..The facts that this event is more frequent after the second dose and it occurs a few days after the inoculation…..suggest an immune-mediated mechanism analogous to an auto-immune reaction. To conclude, the Spike protein acts in a peculiar way, not simply as an immunogen, but as a disease-causing agent”. Further evidence that the COVID-19 vaccines have induced autoimmunity leading to severe diseases can be seen in the [following references: chorea](https://pubmed.ncbi.nlm.nih.gov/37423421/), systemic vasculitis ([Link#1](https://pubmed.ncbi.nlm.nih.gov/37422611/); [Link#2](https://pubmed.ncbi.nlm.nih.gov/36624889/)), [Evans Syndrome](https://pubmed.ncbi.nlm.nih.gov/37406068/), [myocarditis and pericarditis](https://pubmed.ncbi.nlm.nih.gov/37399904/), [morphea](https://pubmed.ncbi.nlm.nih.gov/37397404/), thrombocytopenic purpura/thrombotic thrombocytopenia ([Link#1](https://pubmed.ncbi.nlm.nih.gov/37351233/); [Link#2](https://pubmed.ncbi.nlm.nih.gov/37275917/); [Link#3](https://pubmed.ncbi.nlm.nih.gov/37204726/); [Link#4](https://pubmed.ncbi.nlm.nih.gov/37150909/); [Linl#5](https://pubmed.ncbi.nlm.nih.gov/36855477/)), hepatitis ([Link#1](https://pubmed.ncbi.nlm.nih.gov/37349170/); [Link#2](https://pubmed.ncbi.nlm.nih.gov/37160542/)), [chronic liver disease](https://pubmed.ncbi.nlm.nih.gov/37349170/), [liver injury](https://pubmed.ncbi.nlm.nih.gov/37290592/), [urticarial reactions](https://pubmed.ncbi.nlm.nih.gov/37245259/), [neurological](https://pubmed.ncbi.nlm.nih.gov/37223456/), [lichenoid eruptions](https://pubmed.ncbi.nlm.nih.gov/36851315/), [premature non-communicable diseases](https://pubmed.ncbi.nlm.nih.gov/36851087/), [retroperitoneal fibrosis](https://pubmed.ncbi.nlm.nih.gov/36814401/), [hematologic complications](https://pubmed.ncbi.nlm.nih.gov/36795118/), [diabetes](https://pubmed.ncbi.nlm.nih.gov/36793809/), [autoimmune disorders](https://pubmed.ncbi.nlm.nih.gov/36788969/), [thyroiditis](https://pubmed.ncbi.nlm.nih.gov/36415601/), [aplastic anemia](https://pubmed.ncbi.nlm.nih.gov/36314944/) among many other adverse events.  A more complete picture of the damage done to myriad organs, tissues , and fluids can be found in the following sources: [cancers](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-cancers-rare-events-806312db), [cardiovascular](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-cardiovascular-events-rare-01b2657e), [neurological](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-neurological-events-rare-6adb293f), [autoimmune](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-autoimmune-events-rare-8c55ed90), [endocrine](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-endocrine-events-rare-b4f0ecca), [reproductive-pregnancy](https://www.trialsitenews.com/a/what-is-the-spectrum-of-vaccine-induced-adverse-reproductive-pregnancy-events-54c74757), [blood-lymph](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-blood-lymph-events-rare-792b2541), [gastrointestinal](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-gastrointestinal-events-rare-2c99c76b), and [ear-labyrinth disorders](https://www.trialsitenews.com/a/tinnitus-another-canary-in-the-vaccine-mine.-0620c78c). 1. Concentration in Ovaries A bioweapon that is designed to maim and kill would impact not only those who are exposed to it, but also their children.  The following will show that the COVID-19 vaccine impacts the ovaries (and the testes to some degree), and has the potential to cause damage ranging from infertility and malformation to stillbirth and miscarriages. A **_2012_** study on accumulation of nanocarriers in the ovaries stated: “a potential toxicity risk of all nanoscaled drug delivery systems was found. An accumulation of several structurally different nanocarriers but not of soluble polymers was detected in rodent ovaries after intravenous (i.v.) administration. Studies in different mouse species and Wistar rats were conducted and a high local accumulation of nanoparticles, nanocapsules and nanoemulsions in specific locations of the ovaries [was found in all animals](https://pubmed.ncbi.nlm.nih.gov/22361117/)).” A **_2018_** study on adverse effects of nanoparticles on the reproductive system concluded: “Previous studies have shown that numerous types of NPs are able to pass certain biological barriers and exert toxic effects on crucial organs, such as the brain, liver, and kidney. Only recently, attention has been directed toward the reproductive toxicity of nanomaterials. NPs can pass through the blood-testis barrier, placental barrier, and epithelial barrier, which protect reproductive tissues, and then accumulate in reproductive organs. NP accumulation damages organs (testis, epididymis, ovary, and uterus) by destroying Sertoli cells, Leydig cells, and germ cells, causing reproductive organ dysfunction that adversely affects sperm quality, quantity, morphology, and motility or reduces the number of mature oocytes and disrupts primary and secondary follicular development. In addition, NPs can disrupt the levels of secreted hormones, causing changes in sexual behavior…..possible mechanisms include oxidative stress, apoptosis, inflammation, and genotoxicity. Previous studies have shown that NPs can increase inflammation, oxidative stress, and apoptosis and induce ROS, causing damage at the molecular and genetic levels [which results in cytotoxicity](https://pubmed.ncbi.nlm.nih.gov/30587973/).” A 2021 study on ovarian accumulation of intravenously injected nanoemulsions stated: “**_prepubescent_** mice showed nearly no accumulation of nanoemulsion in their uteri and ovaries, but high accumulations in the organs of the RES liver and spleen independently of the particle size. In **_fertile adult_** mice, the accumulation increased significantly in the ovaries with an increased particle size of the nanoemulsions by nearly doubling the portion of the average radiant efficiency (PARE) to ~10% of the total measured signal of all excised organs. With reproductive aging and hence **_loss of fertility_** in senescent mice, the accumulation decreased again to moderate levels, again independently of the particle size.  In conclusion, the ovarian accumulation of these nanocarriers depended on both the age plus the [particle size during maturity](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347032/).” A 2023 study on the impact of COVID-19 vaccines on pregnancy outcomes and menstrual function concludes: “Analysis of VAERS data shows excessive AEs \[Adverse Events\] for the COVID-19 vaccines as compared with the influenza vaccines by more than a factor of two in almost all cases. According to the CDC, a PRR \[proportional reporting ratio\] of two or greater is a safety signal that requires further study…..newborn death rates are increased, and this is explained by the deleterious effects of the COVID-19 vaccines on pregnancy with increased risk of pregnancy complications, premature deliveries, preeclampsia, PPROM, and increase in fetal growth restriction….The neonatal death rates (newborns dying in the first month of life) in Israel hovered between 4-8 per 1000 live births for 2019 and 2020. Then in the second quarter of 2021, it suddenly jumped three-fold to 17, dipped again in the third quarter, and then jumped again to 18 in the last quarter of 2021…..This study’s results are supported by evidence that the most stunning rises in fetal death (stillbirth) rates are seen in those geographic areas whose cultures and governments aggressively push [COVID-19 vaccines in pregnancy](https://jpands.org/vol28no1/thorp.pdf)” This section ends with excerpts from a recent review article on how the COVID-19 RNA-injections [affect male fertility](https://www.jelsciences.com/articles/jbres1648.pdf). “To protect the administered RNA against degradation by RNases, it is enclosed in LNPs (Lipid NanoParticles), which due to their small size (< 100 nm) are able to pass biological barriers. As LNPs resemble exosomes, they can also take advantage of the natural endocytosis process.…..Accumulation of LNPs in reproductive organs disrupts the hormonal balance and causes inflammation and, therefore, may per se negatively affect reproductive health.…..presence of a variety of modified nucleosides in the manufactured mRNA **_suppresses its intrinsic immune activation_**, while leading to superior protein production for long duration.…..the full length spike protein is presented at the cell surface of the producing cell, hence tagging it with a “foreign label” that **_converts the former healthy cell into an apparent target to be attacked by the immune system_**.…..SARS-CoV-2 RNA can reverse transcribe without reverse transcriptase and, in addition, DNA copies can integrate into the genome of infected human HEK293T cells. Authors reported target site duplications flanking the viral sequences and consensus LINE1 (Long Interspersed Nuclear Element-1) endonuclease recognition sequences at the integration sites suggesting a LINE1-mediated retroposition mechanism. It is well-known that the autonomous retrotransposon LINE1 comprising approx. 17% of the human genome…..can act as an endogenous reverse transcriptase…..and exhibit increased expression upon viral infection…..including SARS-CoV-2.…..COVID-19 m RNA vaccine BNT162b2 is able to enter human Huh7 liver cells and will be reverse transcribed into DNA as fast as six hours following exposure.…..In the case when a cell with an integrated and expressed SARS-CoV-2 sequence survives and presents a viral antigen after infection has already been cleared by the immune system, this might induce permanent stimulation of the immune system and, as a consequence, **_may trigger a condition comparable to that in autoimmunity_**.…..Whether viral genetic information can integrate into human genomic DNA is not a question, but a fact, as up to 8% of the human genome does not derive from our ancestors, but from retroviruses, i.e., HERVs (Human Endogenous RetroViruses).…..RNA-integration into human DNA is feasible in various ways, i.e., via the aforementioned LINE1 reverse transcription or the human reverse transcriptase polymerase-theta.…..Inheritance of viral-derived genome sequences occurs when viral DNA, reverse transcribed from viral RNA, integrates into DNA of a reproductive cell and, subsequently, is **_passed on from father or mother to the offspring._**…..If it should turn out that vaccine-derived RNA, reverse transcribed into DNA, can indeed integrate into a germ cell´s DNA, there is also a **_high likelihood of inheritance and spike protein production in the offspring_**. High LINE1 levels have been reported in sperm, which can reverse transcribe exogenous RNA into DNA and deliver plasmids packaging up this DNA to the oocyte upon fertilization. Subsequently, plasmids will propagate themselves within the embryo…..Due to massive chromatin condensation, sperm is a transcriptionally inactive cell and, therefore, sperm RNAs have for a long time been considered irrelevant remnants of spermatogenesis. However, sperm RNAs have been demonstrated to play an active role in sperm function, fertility and even conception…..While the quantity of RNA in sperm appears to be rather small when compared with the amount in oocytes, it has been reported to be **_sufficient to have an impact on transgenerational inheritance_**.…..nucleic acids encapsulated in exosomes have been reported to distribute throughout the circulation system, pass the blood-testis-barrier and enter sperm…..As LNPs containing the modRNA resemble exosomes, it is highly likely that this will also apply to the administered RNA-based vaccines.…..there are several conceivable pathways how spike proteins in reproductive organs may affect germ cell development and semen quality. To date, nobody knows whether the reported decrease of semen quality after COVID-19 injections represents only a temporary or a long-lasting effect. The fact that men experience a permanent renewal of their germ cells may act to “wash-out” negative environmental exposures and “reset” the original genetic program. However, this strategy will fail, if vaccine-derived RNA, reverse transcribed into DNA, will manage to integrate into a spermatogonial stem cell´s DNA. In this probably rare case, sperm will forward the genetic information for SARS-CoV-2 spike protein to the offspring. As mechanisms regulating sperm-mediated gene transfer upon fertilization and the significance of sperm LINE1 endogenous reverse transcriptase for potential generation of new genetic information that may be forwarded to the offspring are still far from being understood…..scientists and medical doctors must realize that the active ingredient of “mRNA-based vaccines” is not simply a mRNA molecule carrying the information for the synthesis of a specific protein, nota bene an exogenous viral protein, but modRNA specifically designed for translational efficacy and longevity encapsulated in LNPs to bypass biological barriers and get access to all cells including heart and brain…..What is the underlying rationale when an originally healthy cell within heart or brain starts to synthesize a viral protein transforming this cell into a target to be attacked by our immune system?…..mRNA is also involved in the regulation of gene expression…..which is why cells have mechanisms “at hand” to silence mRNA species not required. Theses protective mechanisms, however, will not work with modRNA.” ## DISCUSSION AND CONCLUSIONS The following three key biological mechanisms that resulted in severe damage to the recipients’ organs, tissues, and fluids were activated following COVID-19 vaccination: 1) degradation and suppression of the immune system, 2) induction of pseudo-autoimmunity, and 3) concentration in the ovaries.  The first mechanism would be expected to result in increased numbers and aggressiveness of cancers, re-emergence of dormant viruses, and increased autoimmune diseases.  The second mechanism would be expected to result in increased damage to myriad organs, tissues, and fluids.  The third mechanism would be expected to result in reduced fertility, excessive death of fetuses conceived, and malformations of any children born.  All these predicted adverse events have occurred, in massive numbers unlike any in the history of vaccine administration.  And these effects are for the relatively short-term.  Long-term effects remain to be seen. Whether or not these injections are called bioweapons, the act like bioweapons, producing the types of damage we would expect from bioweapons.  The method of deployment of these injections over the last 2.5 years suggests a proof-of-principle demonstration of the concept rather than an all-out biowarfare attack.  Phase 1 was the fear engendered by convincing the public that a dangerous pandemic was occurring, when in reality the pandemic was a [complete fabrication](https://www.scienceopen.com/document?vid=9ef8d0fc-a3a0-4cba-95ce-a63a67a4ac2c). Phase 2 was the introduction of extreme measures (with no basis in science) that showed the degree of public compliance based on fear from Phase 1.  Phase 3 was the introduction of untested and dangerous vaccines to a compliant public.  Because only about ten percent of the vaccine “lots” appeared to generate most of the serious adverse events, this could have been a deliberate effort to minimize total serious adverse events, which would have dissuaded most of the public from getting vaccinated. As was shown in this Op-ed, most of these biological mechanisms that resulted in damage were known well before the vaccines were distributed to the public.  They were all in the open biomedical literature, accessible to all.  The fact that vaccine manufacturers, politicians, regulatory agencies, mainstream media, doctors, and academics allowed the vaccines to go forward with knowledge of their harmful effects and without adequate safety testing implies collusion among all the mainstream institutions. Most disturbing is the reaction of the American public.  While the compliance could have been excused in the first few months of 2020, by mid-2020 it was evident that, at best, only one demographic was possibly being affected (65+, with comorbidities).  We emphasized that point in our paper, published in mid-September 2021 (see the Appendix for relevant excerpts from the paper).  By mid-2021, it should have been evident to all the authorities and the public that most of the people who took the shots did not need them.  Yet, the American public lined up as told, took shots they did not need, and have suffered copious adverse effects that could have been predicted. Almost as disturbing is the compliance of the medical “profession” in recommending and administering the shots to those for whom there would be no benefit and much potential risk.  While there has been a concerted effort to excuse this compliance because of the fear of losing one’s medical license or certification, and not being able to pay off student loans or support one’s family, there may be other reasons that were higher priority.  For example, examination of adverse effects in VAERS from post-COVID-19 injections shows a plethora of symptoms across all organs, tissues, and fluids ([cancers](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-cancers-rare-events-806312db), [cardiovascular](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-cardiovascular-events-rare-01b2657e), [neurological](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-neurological-events-rare-6adb293f), [autoimmune](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-autoimmune-events-rare-8c55ed90), [endocrine](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-endocrine-events-rare-b4f0ecca), [reproductive-pregnancy](https://www.trialsitenews.com/a/what-is-the-spectrum-of-vaccine-induced-adverse-reproductive-pregnancy-events-54c74757), [blood-lymph](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-blood-lymph-events-rare-792b2541), [gastrointestinal](https://www.trialsitenews.com/a/are-covid-19-vaccine-induced-adverse-gastrointestinal-events-rare-2c99c76b), and [ear-labyrinth disorders](https://www.trialsitenews.com/a/tinnitus-another-canary-in-the-vaccine-mine.-0620c78c)). Given the extent of these short-mid-term symptoms, and the prospect of serious long-term symptoms from diseases with long lag times like autoimmune diseases and cancers, the doctors who specialize in any of these diseases/symptoms (e.g., oncologists, cardiologists, neurologists, nephrologists, gynecologists, hematologists, gastroenterologists, etc.) will experience a financial windfall as far as the eye can see.  In my view, the financial payoffs from administering and recommending these shots outweighed the desire to “first, do no harm” for many of these practitioners (not for all; there are those who took their Hippocratic oath seriously, and risked their reputations and finances to tell the truth about these shots). To conclude, whatever we call these shots, they have all the characteristics of a bioweapon, and they have achieved the results one would expect of a proof-of-principle demonstration of a bioweapon.  Unless the American public takes appropriate action now, a full-scale deployment of mRNA-based injections at full strength could occur in the relatively near future, leading to even greater catastrophic results than those that have occurred already. # GPT summary ## SUMMARY Dr. Ronald N. Kostoff's analysis scrutinises the biological mechanisms, impacts, and potential intent behind the COVID-19 vaccinations. He suggests that the adverse health effects observed post-vaccination, including higher disease and injury rates, align with the characteristics of a bioweapon. The article delves into the suppression of the immune system, induction of pseudo-autoimmunity, and the vaccines' concentration in ovaries, which could lead to a broad spectrum of health issues like increased cancer rates, organ and tissue damage, and reproductive harm. Kostoff posits that the deployment of these vaccines could be a proof-of-principle for biowarfare, highlighting the need for public action to prevent future catastrophes. ## IDEAS 1. COVID-19 vaccinations have been associated with significant adverse health effects, raising questions about their development, contents, and impact on human health. 2. Evidence from various databases indicates higher rates of diseases and economic consequences for vaccinated individuals compared to the unvaccinated. 3. The term "bioweapon" implies intent, and while intent cannot be proven, the damage following vaccination suggests a bioweapon-like impact. 4. Known adverse mechanisms from COVID-19 vaccinations include immune system degradation, pseudo-autoimmunity, and organ concentration. 5. The suppression of toll-like receptors, key in cancer surveillance, may have been compromised by the mRNA vaccines. 6. COVID-19 vaccinations may alter T-cell signaling, impairing cancer surveillance and increasing cancer risks. 7. The vaccines could induce IgG4, which may inhibit the immune system's ability to combat cancer. 8. Spike proteins from the vaccines may interfere with DNA repair mechanisms, potentially leading to chronic diseases like cancer. 9. Contaminants in the vaccines, such as plasmid DNA and SV40, could pose severe health risks, including the promotion of malignant diseases. 10. The vaccines may enhance the expression of PD-L1 on immune cells, a known risk factor for poor cancer outcomes. 11. COVID-19 vaccinations could induce autoimmune responses, leading to widespread organ and tissue damage. 12. The vaccines' concentration in ovaries raises concerns about fertility, fetal health, and potential transgenerational effects. 13. The vaccines' ability to act as a bioweapon is evidenced by the extensive range of adverse health effects documented. 14. The rollout of the vaccines may have been a controlled demonstration rather than a full-scale biowarfare attack. 15. The American public's compliance with vaccination, despite emerging evidence of harm, is concerning and requires urgent action. 16. The medical profession's participation in administering the vaccines, potentially motivated by financial incentives, conflicts with the principle of "do no harm." 17. The potential for mRNA-based injections to be deployed on a larger scale in the future could lead to more catastrophic health outcomes. 18. Public awareness and action are crucial to preventing the misuse of vaccine technology as a bioweapon. ## QUOTES 1. "The evidence makes clear that those who received these injections have experienced much higher rates of myriad diseases and injuries and much higher adverse economic consequences than those who did not receive the injections." 2. "Labelling a disease-causing organism and its delivery system as a bioweapon implies intent." 3. "The act like bioweapons, producing the types of damage we would expect from bioweapons." 4. "The method of deployment of these injections over the last 2.5 years suggests a proof-of-principle demonstration of the concept rather than an all-out biowarfare attack." 5. "By mid-2021, it should have been evident to all the authorities and the public that most of the people who took the shots did not need them." 6. "The fact that vaccine manufacturers, politicians, regulatory agencies, mainstream media, doctors, and academics allowed the vaccines to go forward with knowledge of their harmful effects and without adequate safety testing implies collusion among all the mainstream institutions." 7. "The financial payoffs from administering and recommending these shots outweighed the desire to 'first, do no harm' for many of these practitioners." 8. "Whatever we call these shots, they have all the characteristics of a bioweapon, and they have achieved the results one would expect of a proof-of-principle demonstration of a bioweapon." 9. "Unless the American public takes appropriate action now, a full-scale deployment of mRNA-based injections at full strength could occur in the relatively near future, leading to even greater catastrophic results than those that have occurred already." ## HABITS 1. Dr. Kostoff habitually scrutinises biomedical literature and databases to inform his analysis of vaccine-related adverse events. 2. He consistently applies a critical perspective on the intent and consequences of health interventions, such as vaccines. 3. Kostoff maintains a practice of cross-referencing scientific studies to support his arguments regarding the potential risks of vaccinations. ## FACTS 1. VAERS and other databases have documented higher disease rates and adverse economic consequences among vaccinated individuals. 2. The mRNA vaccines contain pseudouridine-modified mRNA, which can suppress immune system activity. 3. COVID-19 vaccinations have been shown to increase serum levels of IgG4, potentially impairing cancer surveillance. 4. Studies suggest that the spike protein produced by COVID-19 vaccinations may interfere with DNA repair mechanisms. 5. Contaminants found in vaccine vials, such as plasmid DNA and SV40, have been associated with the potential induction of malignant diseases. 6. The COVID-19 vaccines have been associated with an increase in newborn death rates in certain regions. 7. Nanoparticles, such as those used in vaccine delivery systems, have been found to accumulate in reproductive organs and disrupt hormonal balance. 8. The COVID-19 vaccines have been linked to immune system suppression and the induction of autoimmune diseases. 9. Research indicates that the mRNA from vaccines can be reverse-transcribed and integrated into the human genome. ## REFERENCES 1. The Epoch Times articles and interviews with Dr. William Makis and Dr. Ryan Cole on the potential causes of increased cancer rates post-vaccination. 2. Scientific studies and reviews that discuss the suppression of the immune system, induction of pseudo-autoimmunity, and the vaccines' concentration in ovaries. 3. VAERS and other international adverse event tracking databases that provide evidence of vaccine-related health impacts. 4. Dr. Sucharit Bhakdi's video explanations of vaccine-induced damage to the endothelium and organs. 5. Articles on the immune response and molecular mechanisms of cardiovascular adverse effects of spike proteins from SARS-CoV-2 and mRNA vaccines. 6. Autopsy reports and studies that detail the extent of vaccine-induced damage across various organs and tissues. ## RECOMMENDATIONS 1. Public awareness campaigns should be initiated to inform citizens about the potential risks associated with COVID-19 vaccinations. 2. Independent investigations into the development and approval processes of COVID-19 vaccines are needed to ensure transparency and accountability. 3. Healthcare professionals should be encouraged to critically evaluate vaccine recommendations and consider individual patient risk profiles before administering vaccinations. 4. Further research into the long-term effects of COVID-19 vaccinations on human health, including reproductive and genetic implications, is essential. 5. Policy reviews and reforms are necessary to ensure that vaccine deployment is based on sound scientific evidence and ethical considerations. 6. Support systems should be established for individuals who have experienced adverse health effects following COVID-19 vaccinations. 7. Legal frameworks must be developed to protect whistleblowers and medical professionals who raise concerns about vaccine safety. 8. International collaboration is needed to monitor and respond to potential bioweapon threats posed by novel medical interventions like mRNA vaccines.